Risk factors for Clostridioides difficile infection caused by ribotype 027 strains in the Veterans Affairs Healthcare System: a matched case-control study
Antimicrobial stewardship interventions focused on fluoroquinolones and macrolides could be beneficial in reducing the risk for infection due to the ribotype 027 C. difficile strain. Several other factors could potentially be used to identify patients at increased risk for CDI due to the ribotype 027 strain, but further studies are needed to assess their utility in clinical settings.
Authors
- Sandra Y. Silva
- Curtis J. Donskey (ORCID: https://orcid.org/0000-0003-0990-4498)
- Brigid Wilson (ORCID: https://orcid.org/0000-0003-2966-2940)
Institutions
- Geriatric Research Education and Clinical Center (US)
- Louis Stokes Cleveland VA Medical Center (US)
- University School (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Antimicrobial Resistance and Infection Control
- Published
- 2025-05-16
- DOI
- https://doi.org/10.1186/s13756-025-01571-0
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Veterans Affairs