Acute Promyelocytic Leukemia Diagnosed Due to Pericoronitis: A Case Report

Herein, we report the case of a 60-year-old female patient diagnosed with acute promyelocytic leukemia (APL) following pericoronitis. The patient was referred to our department for the extraction of a wisdom tooth. On initial examination, tissue swelling and necrosis were observed in the gingiva around the right mandibular wisdom tooth. After 1 week of no improvement, purpura were observed on the patient's forearms and lower legs, signifying the presence of a blood disorder. Following the detection of pancytopenia, the patient was referred to the Department of Hematology and Oncology. Bone marrow aspiration confirmed the diagnosis of APL. Chemotherapy with all-trans retinoic acid was started immediately, and the patient is currently in complete molecular remission. The mandibular wisdom tooth was extracted after complete molecular remission and the patient is doing well.

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Journal
Yonago acta medica
Published
2025-01-01
DOI
https://doi.org/10.33160/yam.2025.05.010
Primary Topic
Retinoids in leukemia and cellular processes
Type
article
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0.00
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article

Acute Promyelocytic Leukemia Diagnosed Due to Pericoronitis: A Case Report

Isamu Kodani, Takayuki Shingu, Makoto Kawasaki, Yu Yoshida
Yonago acta medica
Retinoids in leukemia and cellular processes
article

Acute Promyelocytic Leukemia Diagnosed Due to Pericoronitis: A Case Report

Isamu Kodani, Takayuki Shingu, Makoto Kawasaki, Yu Yoshida
article en

Abstract

Herein, we report the case of a 60-year-old female patient diagnosed with acute promyelocytic leukemia (APL) following pericoronitis. The patient was referred to our department for the extraction of a wisdom tooth. On initial examination, tissue swelling and necrosis were observed in the gingiva around the right mandibular wisdom tooth. After 1 week of no improvement, purpura were observed on the patient's forearms and lower legs, signifying the presence of a blood disorder. Following the detection of pancytopenia, the patient was referred to the Department of Hematology and Oncology. Bone marrow aspiration confirmed the diagnosis of APL. Chemotherapy with all-trans retinoic acid was started immediately, and the patient is currently in complete molecular remission. The mandibular wisdom tooth was extracted after complete molecular remission and the patient is doing well.

Yonago acta medicaVol. 68(2)
National Institute of Technology, Yonago College (JP), National Hospital Organization (JP), YKK (Japan) (JP), Tottori University (JP)
Good health and well-being
Openalex Percentile: Top 90%
Retinoids in leukemia and cellular processes
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Acute Promyelocytic Leukemia Diagnosed Due to Pericoronitis: A Case Report — Isamu Kodani, Takayuki Shingu, et al. · Yonago acta medica (2025) | TGRS Research Map | TGRS