Association of left ventricular systolic dysfunction with outcome following pediatric traumatic brain injury
Nearly 35% of pediatric TBI patients who underwent transthoracic echocardiography were found to have LVSD within 72 hours of admission. Low admission GCS score, abusive head trauma, or cardiac arrest significantly increased the risk of LVSD on univariate analysis, while the GCS score was a risk factor on multivariate analysis. The presence of LVSD was associated with an increased risk of mortality and morbidity in survivors on univariate analysis. Future prospective studies are warranted to further characterize myocardial dysfunction in pediatric patients with TBI and determine whether earlier recognition and treatment might improve outcomes.
Authors
- Adam S. Himebauch (ORCID: https://orcid.org/0000-0003-1848-2477)
- Todd J. Kilbaugh (ORCID: https://orcid.org/0000-0002-4959-3092)
- Vanessa Mazandi (ORCID: https://orcid.org/0000-0003-3671-5422)
- Thomas Conlon (ORCID: https://orcid.org/0000-0002-0703-484X)
- Chongtae Kim (ORCID: https://orcid.org/0009-0003-2483-806X)
- Christie Glau (ORCID: https://orcid.org/0000-0003-1583-4609)
- Kaitlyn Boggs (ORCID: https://orcid.org/0000-0003-4135-3809)
- E. Gabriel (ORCID: https://orcid.org/0000-0002-3931-095X)
- Kumaran Senthil (ORCID: https://orcid.org/0000-0003-0636-3470)
- Jimmy W. Huh (ORCID: https://orcid.org/0000-0003-4268-4829)
- Nankee Kumar
- Shih-Shan Lang
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of Neurosurgery Pediatrics
- Published
- 2025-05-16
- DOI
- https://doi.org/10.3171/2025.3.peds24655
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00