Palpebral schwannoma as an uncommon differential diagnosis in solid eyelid lesions

Schwannoma (neurilemmoma) is a rare benign tumor that originates from Schwann cells of peripheral nerves, accounting for approximately 0.1 to 0.7% of eyelid tumors. The occurrence of schwannoma in the eyelid is extremely rare, with very few cases reported in the literature to date. These tumors are typically solitary, asymptomatic, and slow-growing, which can make early diagnosis challenging. Clinically, they present as solid eyelid masses without skin involvement and can be mistaken for other conditions such as inclusion cysts, recurrent chalazia, or other types of tumors. A definitive diagnosis is obtained through histopathological and immunohistochemical studies. The treatment of choice is complete surgical excision, which generally has a favorable prognosis with a low recurrence rate. This case highlights the importance of always considering schwannomas in the differential diagnosis of any solid eyelid lesion.

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Publication Details

Journal
International Surgery Journal
Published
2025-05-16
DOI
https://doi.org/10.18203/2349-2902.isj20251441
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

Palpebral schwannoma as an uncommon differential diagnosis in solid eyelid lesions

Diana Guadalupe González Guzmán, N. Gascón, J. Flores, Iván González et al.
International Surgery Journal
Neurofibromatosis and Schwannoma Cases
article

Palpebral schwannoma as an uncommon differential diagnosis in solid eyelid lesions

Diana Guadalupe González Guzmán, N. Gascón, J. Flores, Iván González, Oscar J. Martínez, Cristina Maria Mendes Andrade, D. González, Brittani Trejo
article en

Abstract

Schwannoma (neurilemmoma) is a rare benign tumor that originates from Schwann cells of peripheral nerves, accounting for approximately 0.1 to 0.7% of eyelid tumors. The occurrence of schwannoma in the eyelid is extremely rare, with very few cases reported in the literature to date. These tumors are typically solitary, asymptomatic, and slow-growing, which can make early diagnosis challenging. Clinically, they present as solid eyelid masses without skin involvement and can be mistaken for other conditions such as inclusion cysts, recurrent chalazia, or other types of tumors. A definitive diagnosis is obtained through histopathological and immunohistochemical studies. The treatment of choice is complete surgical excision, which generally has a favorable prognosis with a low recurrence rate. This case highlights the importance of always considering schwannomas in the differential diagnosis of any solid eyelid lesion.

International Surgery Journal
Universidad Autónoma del Estado de Hidalgo (MX), Universidad Autónoma de Nuevo León (MX), Autonomous University of Yucatán (MX), Hospital General de México (MX), Universidad Regional del Sureste (MX), Hospital Español (MX), Universidad Latina de México (MX), Hospital de Especialidades (MX)
Openalex Percentile: Top 82%
Neurofibromatosis and Schwannoma Cases
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Palpebral schwannoma as an uncommon differential diagnosis in solid eyelid lesions — Diana Guadalupe González Guzmán, N. Gascón, et al. · International Surgery Journal (2025) | TGRS Research Map | TGRS