Ergothioneine Suppresses Amyloid β-Induced Tau Phosphorylation and Cytotoxicity by Inactivating Glycogen Synthase Kinase-3β in Cultured Neurons
ERGO may suppress the increased expression of p-Tau and proteins involved in Aβ production induced by Aβ oligomers by inactivating GSK-3β, thereby mitigating neurotoxicity.
Authors
- Satoshi Matsumoto (ORCID: https://orcid.org/0000-0003-4836-7170)
- Noritaka Nakamichi (ORCID: https://orcid.org/0000-0002-0283-3546)
- Yuichiro Hayashi (ORCID: https://orcid.org/0000-0001-9870-0053)
- Fumiya Shibagaki (ORCID: https://orcid.org/0000-0001-5434-9257)
Institutions
- Takasaki University of Health and Welfare (JP)
Publication Details
- Journal
- Current Molecular Pharmacology
- Published
- 2025-06-02
- DOI
- https://doi.org/10.2174/0118761429387340250507055903
- Citations
- 2
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Ministry of Education, Culture, Sports, Science and Technology