The optimal slice to quantify the volumes of subcutaneous adipose tissue and skeletal muscle on chest computed tomography as imaging marker for body composition estimation

Considering measurement simplicity and accuracy, the aortic arch slice was identified as the optimal single slice for predicting total thoracic SAT and SM volumes. Additionally, the clinical significance of SAT and SM area at this slice was verified with lung function in COPD patients. Key messages What is already known on this topic: Specific abdominal slices have been shown to estimate abdominal volumes accurately, while the optimal slice to predict thoracic volumes is uncertain. What this study adds: To identify the optimal slice for simultaneously predicting both thoracic SAT and SM volumes. How this study might affect research, practice or policy: The optimal slice in the chest for measurement is crucial for advancing research on thoracic SAT and SM.