[Effect of stretch on taurine upregulated gene 1-mediated miR-545-3p/cannbinoida receptor 2 pathway regulating distraction osteogenesis in rats].
Under the action of stretch, the expression of TUG1 in the femoral distraction area of rats increases, which promotes the expression of CNR2 by inhibiting the expression of miR-545-3P, which is helpful to the mineralization of the extension area and osteogenesis.
Authors
- Yongxin Zheng (ORCID: https://orcid.org/0000-0002-2844-7985)
- Yalong Wu (ORCID: https://orcid.org/0000-0001-9879-431X)
- Mengzhu Zhang (ORCID: https://orcid.org/0000-0002-8254-6802)
- Bin Wang (ORCID: https://orcid.org/0000-0001-7419-5080)
- Zixin Wang (ORCID: https://orcid.org/0009-0000-3217-8629)
Institutions
- North China University of Science and Technology (CN)
- Second Hospital of Tangshan (CN)
- North China University of Science and Technology Affiliated Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-05-15
- DOI
- https://doi.org/10.7507/1002-1892.202503010
- Primary Topic
- Aldose Reductase and Taurine
- Type
- article