Usage of 3D-Printed Scaffolds Manufactured with Bio-Based Photopolymer Resin Via 3D DLP in Tissue Engineering
Abstract In this study, three-dimensional (3D) printed scaffolds were fabricated using a bio-based photopolymer resin derived from sustainable resources for tissue engineering applications. The resin consisted of a UV-curable bio-based fatty acid-based polyester acrylate, polyethylene glycol dimethacrylate, and a photoinitiator. To enhance porosity and biodegradability, coconut oil and poly(ethylene glycol) (PEG) were incorporated into the formulations. The curing behavior of different formulations was investigated by differential photocalorimetry (Photo-DSC), and it was observed that polyethylene glycol accelerated the curing process. The biocompatibility of the 3D printed scaffolds was evaluated using culture experiments with mouse fibroblast (L-929) cells. The obtained results demonstrate that the developed bio-based photopolymer resins have the potential to be a promising material for tissue engineering applications. Graphical Abstract
Authors
- Sibel Çetinel (ORCID: https://orcid.org/0000-0003-0248-9447)
- Özge Tezel (ORCID: https://orcid.org/0000-0002-5791-1812)
- Memet Vezi̇r Kahraman (ORCID: https://orcid.org/0000-0003-1043-6476)
- Ayşegül Açıksarı
- Ramazan Ceylan
- Ebru Demir (ORCID: https://orcid.org/0000-0002-9369-4149)
Institutions
- Sabancı Üniversitesi (TR)
- Türkisch-Deutsche Universität (TR)
- Marmara University (TR)
Publication Details
- Journal
- Journal of Polymers and the Environment
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1007/s10924-025-03592-7
- Citations
- 2
- Primary Topic
- Additive Manufacturing and 3D Printing Technologies
- Type
- article
- Field-Weighted Citation Impact
- 1.37
Funders
- Marmara Üniversitesi