Scutellaria Baicalensis Georgi in the Suppression of Colorectal Cancer Through Modulation of the Intestinal Flora

Colorectal cancer (CRC) is a common malignant tumor worldwide, and its incidence and mortality are growing year by year. In recent years, the beginning and course of CRC are directly linked to intestinal flora imbalance, according to an increasing number of research.Therefore, finding a unique treatment approach and direction that can regulate the intestinal flora is therefore urgently needed. Traditional Chinese medicine as an adjuvant therapy for CRC has the characteristics of multi-targets, multi-levels, multi-links, and overall regulation, and it has significant advantages in the prevention and management of CRC.Scutellaria baicalensis Georgi (SBG), as one of the main drugs in the utilisation of traditional Chinese medicine as an adjuvant therapy for CRC, has been widely studied and recognised. Studies have shown that SBG and its active ingredients can aid in the prevention and management of CRC by regulating the intestinal flora, improving the imbalance of the flora, inhibiting the proliferation of harmful microorganisms, and enhancing the function of advantageous microorganisms. In addition, scutellaria can also inhibit the incidence and development of CRC by inhibiting inflammatory response, inducing apoptosis of cancer cells and blocking signaling pathways