A glutamine metabolism gene signature with prognostic and predictive value for colorectal cancer survival and immunotherapy response
The authors innovatively constructed GLMscore, a robust scoring system in quantifying CRC patients, exploring the distinct biological features, tumor immune microenvironment and microbiome ecology, exhibiting high validity in predicting survival prognosis and clinical treatment efficacy.
Authors
- Yinmeng Zhang (ORCID: https://orcid.org/0009-0001-9486-2466)
- Hongxia Xu (ORCID: https://orcid.org/0000-0001-5215-734X)
- Jiahui Zhao (ORCID: https://orcid.org/0009-0006-4620-7738)
- Jiawei Fan (ORCID: https://orcid.org/0009-0007-4559-4657)
- He Zhu (ORCID: https://orcid.org/0000-0002-5764-5008)
- Yan Xia (ORCID: https://orcid.org/0000-0003-4509-0137)
- Nan Zhang (ORCID: https://orcid.org/0000-0002-7256-4249)
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fmolb.2025.1599141
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05