Clinical evaluation of an in-house Xpert Lysate-based Method combined with MALDI-TOF MS for the rapid identification of positive blood cultures
The method of directly identifying microbial pellets using MALDI-TOF MS, extracted via the Xpert Lysate-based Method we developed, is non-inferior to the conventional Culture Method in terms of ID performance. Meanwhile, it is easy to operate and more time-efficient, making it suitable for routine workflow in the rapid etiological ID of PBCs.
Authors
- Jun Lu (ORCID: https://orcid.org/0000-0002-8459-4867)
- Yili Ping (ORCID: https://orcid.org/0000-0003-4254-3874)
- Zhejiong Wang (ORCID: https://orcid.org/0009-0004-8297-4745)
- Xiling Sun
- Qiong Chen (ORCID: https://orcid.org/0000-0002-2534-8834)
- Haiyan Wang (ORCID: https://orcid.org/0000-0002-3994-5728)
- Junmin Cao
- Shaohua Lin (ORCID: https://orcid.org/0000-0002-3721-0744)
- Bingwei Zhu
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s12866-025-03996-4
- Citations
- 1
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 1.32
Funders
- Zhejiang Chinese Medical University
- Medical Science and Technology Project of Zhejiang Province
- Science and Technology Program of Zhejiang Province