Combined 6th and 12th Cranial Nerve Palsies (Godtfredsen Syndrome) due to Clival Lesions

GS is a combination of CN 6th and 12th palsies and most commonly is due to a lesion in the clivus. Clinicians should be aware of this uncommon combination of cranial nerve findings, the localizing significance, and the differential diagnosis of clival lesions.

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Publication Details

Journal
Journal of Neuro-Ophthalmology
Published
2025-05-15
DOI
https://doi.org/10.1097/wno.0000000000002233
Primary Topic
Head and Neck Surgical Oncology
Type
article
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article

Combined 6th and 12th Cranial Nerve Palsies (Godtfredsen Syndrome) due to Clival Lesions

Sibi Rajendran, Ryu Ishihara, Ardalan Sharifi, Zhenyang Zhao et al.
Journal of Neuro-Ophthalmology
Head and Neck Surgical Oncology
article

Combined 6th and 12th Cranial Nerve Palsies (Godtfredsen Syndrome) due to Clival Lesions

Sibi Rajendran, Ryu Ishihara, Ardalan Sharifi, Zhenyang Zhao, Alexander M. Tseng, Andrew G. Lee, David S. Baskin, Zachary DeZeeuw
article en

Abstract

GS is a combination of CN 6th and 12th palsies and most commonly is due to a lesion in the clivus. Clinicians should be aware of this uncommon combination of cranial nerve findings, the localizing significance, and the differential diagnosis of clival lesions.

Journal of Neuro-OphthalmologyVol. 46(1)
Cornell University (US), Methodist Hospital (US)
Good health and well-being
Openalex Percentile: Top 81%
Head and Neck Surgical Oncology
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