Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

This study will contribute to our understanding of the pathogenesis of HLF and offer possible targets for the treatment of fibrotic diseases.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-05-15
DOI
https://doi.org/10.3389/fimmu.2025.1569296
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

Xinyu Feng, Qinghong Ma, Yongxin Chen, Chao Sun et al.
Frontiers in Immunology
Pulmonary Hypertension Research and Treatments
article

Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

Xinyu Feng, Qinghong Ma, Yongxin Chen, Chao Sun, Jue Zhang
article en

Abstract

This study will contribute to our understanding of the pathogenesis of HLF and offer possible targets for the treatment of fibrotic diseases.

Frontiers in ImmunologyVol. 16
Nanjing Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Jiangsu Province
Openalex Percentile: Top 82%
Pulmonary Hypertension Research and Treatments
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