Chronic BPAF exposure differentially enhances fat deposition in mice fed normal or high-fat diets via lipid metabolism dysregulation
Chronic BPAF exposure differentially exacerbates fat deposition in mice fed normal or high-fat diets via affecting lipid metabolism. Given the widespread prevalence of obesity and the pervasive environmental presence of BPAF, our findings provide valuable insights into the metabolic toxicity of BPAF, thereby raise further concern on the safe utilization and precision prevention of this unique chemical.
Authors
- Xinyue Xu
- Guodong Jia (ORCID: https://orcid.org/0000-0002-8360-0460)
- Yuxuan Wu (ORCID: https://orcid.org/0000-0001-9844-423X)
- Dan Wang (ORCID: https://orcid.org/0000-0002-8701-0804)
- Changfeng Peng (ORCID: https://orcid.org/0000-0002-1249-957X)
- Zhi Tang (ORCID: https://orcid.org/0000-0002-1433-711X)
- Liang Yin (ORCID: https://orcid.org/0000-0003-4745-9196)
- Ying Chen (ORCID: https://orcid.org/0000-0002-0319-4950)
- Yajie Guo (ORCID: https://orcid.org/0009-0006-7881-4532)
- Sang Dan
- Suli Huang (ORCID: https://orcid.org/0000-0003-3864-308X)
- Xiaoxiao Hu (ORCID: https://orcid.org/0000-0001-5216-4777)
- Guangnan Liu (ORCID: https://orcid.org/0000-0003-4209-9574)
- Ziquan Lv (ORCID: https://orcid.org/0009-0008-6069-5867)
Institutions
- Sun Yat-sen University (CN)
- Guangdong Medical College (CN)
- Shenzhen Center for Disease Control and Prevention (CN)
- Shenzhen University Health Science Center (CN)
- Eighth Affiliated Hospital of Sun Yat-sen University
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fendo.2025.1571076
- Citations
- 1
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- National Science and Technology Major Project
- Sanming Project of Medicine in Shenzhen