Case Report: Atypical Imaging Findings of Leptomeningeal Disease in EGFR-Mutated Non-Small Cell Lung Cancer

Leptomeningeal disease (LMD) is a severe complication of metastatic cancer and is particularly prevalent in patients with epidermal growth factor receptor‐mutated non-small cell lung cancer (NSCLC). While MRI is crucial for early detection, classic imaging findings of LMD may be absent. This report presents the case of a 63-year-old woman with epidermal growth factor receptor‐mutated NSCLC exhibiting atypical findings of LMD on MRI, emphasizing the need to recognize unusual imaging patterns for timely diagnosis and management.

Authors

Publication Details

Journal
Neurographics
Published
2025-04-01
DOI
https://doi.org/10.3174/ng.2400041
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00
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article

Case Report: Atypical Imaging Findings of Leptomeningeal Disease in EGFR-Mutated Non-Small Cell Lung Cancer

Tom Geisbush, S.S. Hashmi
Neurographics
Lung Cancer Treatments and Mutations
article

Case Report: Atypical Imaging Findings of Leptomeningeal Disease in EGFR-Mutated Non-Small Cell Lung Cancer

Tom Geisbush, S.S. Hashmi
article en

Abstract

Leptomeningeal disease (LMD) is a severe complication of metastatic cancer and is particularly prevalent in patients with epidermal growth factor receptor‐mutated non-small cell lung cancer (NSCLC). While MRI is crucial for early detection, classic imaging findings of LMD may be absent. This report presents the case of a 63-year-old woman with epidermal growth factor receptor‐mutated NSCLC exhibiting atypical findings of LMD on MRI, emphasizing the need to recognize unusual imaging patterns for timely diagnosis and management.

NeurographicsVol. 15(2)
Openalex Percentile: Top 82%
Lung Cancer Treatments and Mutations
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