Individual patient data meta-analysis of placebo-controlled trials of selective serotonin reuptake inhibitors submitted for regulatory approval in adult obsessive–compulsive disorder
Our IPDMA showed that SSRIs are well accepted and superior to placebo for treating OCD. The effects are modest and independent of baseline patient characteristics.
Authors
- Damiaan Denys (ORCID: https://orcid.org/0000-0002-3191-3844)
- Jasper B. Zantvoord (ORCID: https://orcid.org/0000-0002-6475-902X)
- Taina Mattila
- Anthonius de Boer (ORCID: https://orcid.org/0000-0002-9485-8037)
- Sem E Cohen (ORCID: https://orcid.org/0000-0002-9733-6146)
- Bram W C Storosum (ORCID: https://orcid.org/0000-0002-0764-8745)
Institutions
- Amsterdam Neuroscience (NL)
- Arkin (NL)
- Medicines Evaluation Board (NL)
- Reinier van Arkel (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- The British Journal of Psychiatry
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1192/bjp.2025.87
- Citations
- 4
- Primary Topic
- Obsessive-Compulsive Spectrum Disorders
- Type
- article
- Field-Weighted Citation Impact
- 9.23