Serum levels of miR-21, miR-23a, miR-142-5p, and miR-126 in chronic failure with reduced ejection fraction: a case-control study
Our findings revealed that the levels of miR-21-5p, miR-23a-3p, miR-142-5p,and miR-126-3p were significantly higher among HFrEF patients compared to healthy controls. Further exploration of these miRNAs may lead to new diagnostic, prognostic, and therapeutic options for HF patients.
Authors
- Radka Šigutová (ORCID: https://orcid.org/0000-0002-3259-9009)
- Patrik Šulc
- Lukáš Evin
- David Stejskal (ORCID: https://orcid.org/0000-0003-1204-0395)
- J. Václavík (ORCID: https://orcid.org/0000-0001-7847-0967)
- Eliška Kufová
- Marian Branny
Institutions
- University of Ostrava (CZ)
- University Hospital Ostrava (CZ)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fcvm.2025.1529451
- Citations
- 4
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 3.75