Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning

This study identified CCR5, CYSLTR1, and KLRG1 as efficient diagnostic biomarkers for severe COVID-19 using machine learning and revealed immune regulatory features across COVID-19 progression and recovery.

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Institutions

Publication Details

Journal
Frontiers in Genetics
Published
2025-05-15
DOI
https://doi.org/10.3389/fgene.2025.1599867
Citations
2
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
2.79
Controls
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article

Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning

Zhiyuan Gong, An He
2 citations
Frontiers in Genetics
COVID-19 Clinical Research Studies
2.79
article

Integrated transcriptomic analysis of COVID-19 stages and recovery: insights into key gene signatures, immune features, and diagnostic biomarkers through machine learning

Zhiyuan Gong, An He
article en
2 citations

Abstract

This study identified CCR5, CYSLTR1, and KLRG1 as efficient diagnostic biomarkers for severe COVID-19 using machine learning and revealed immune regulatory features across COVID-19 progression and recovery.

Frontiers in GeneticsVol. 16
Nankai University (CN), Tianjin First Center Hospital (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 11%
COVID-19 Clinical Research Studies
2.79
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