Characterizing hub biomarkers for metabolic-induced endothelial dysfunction and unveiling their regulatory roles in EndMT through RNA sequencing and machine learning approaches
This study identified novel biomarkers for ED. These findings may provide both a potential biomarker and therapeutic target for the prevention and treatment of atherosclerosis and CAD.
Authors
- Liang Xie (ORCID: https://orcid.org/0000-0001-6308-2654)
- Wei Chen (ORCID: https://orcid.org/0000-0003-3233-8877)
- Qi Sun (ORCID: https://orcid.org/0000-0001-5153-6698)
- Peng Wang (ORCID: https://orcid.org/0000-0003-4666-9706)
- Qiang Yang (ORCID: https://orcid.org/0000-0001-5059-8360)
- Yijun Tang (ORCID: https://orcid.org/0000-0002-1928-6446)
- Chunyan Peng (ORCID: https://orcid.org/0009-0001-8289-5092)
- An He (ORCID: https://orcid.org/0000-0003-2899-1419)
Institutions
- Hubei University of Medicine (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fcvm.2025.1585030
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hubei Province