Chronic administration of prebiotics and probiotics prevent pathophysiological hallmarks of Alzheimer’s disease in the cortex of APP/PS1 mice
These data confirm that prolonged dietary regimen enriched with pre- and probiotics counteracts many of the histopathological hallmarks of AD, and poses the bases for a simple, affordable treatment that may help prevent AD.
Authors
- Maria Grazia Giovannini (ORCID: https://orcid.org/0000-0003-4563-0420)
- Chiara Traini (ORCID: https://orcid.org/0000-0002-8314-9366)
- Maria Giuliana Vannucchi (ORCID: https://orcid.org/0000-0002-1060-5025)
- Giada Magni (ORCID: https://orcid.org/0000-0003-2736-9150)
- Daniele Lana (ORCID: https://orcid.org/0000-0002-5193-0019)
- Selene Attorre
- Giorgia Sarti
- Giorgio Tognozzi
- Edoardo Calussi
Institutions
- Azienda Ospedaliero-Universitaria Careggi (IT)
- University of Florence (IT)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fphar.2025.1596469
- Citations
- 6
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- Banca d'Italia