Extremely high HDL cholesterol paradoxically increases the risk of all-cause mortality in non-diabetic males from the Korean population: Korean genome and epidemiology study-health examinees (KoGES-HEXA) cohorts
Extremely high HDL-C levels could paradoxically increase the risk of all-cause mortality, particularly among males, in the general population without type 2 diabetes mellitus. Non-protective effects of very high HDL-C level should be noted when predicting incident metabolic syndrome, particularly in men, in clinical settings.
Authors
- Seokjae Heo (ORCID: https://orcid.org/0000-0002-8502-8330)
- Byoungjin Park (ORCID: https://orcid.org/0000-0003-1733-5301)
- Dong‐Hyuk Jung (ORCID: https://orcid.org/0000-0002-3411-0676)
- Ha Eun Ryu (ORCID: https://orcid.org/0000-0002-7211-9882)
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
- Gangnam Severance Hospital (KR)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fmed.2025.1534524
- Citations
- 6
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 7.77
Funders
- National Research Foundation
- Ministry of Science and ICT, South Korea