Cultivating the Scientific Spirit through the “Advanced Organic Chemistry” —A Case Study of Sharpless Asymmetric Synthesis

The spirit of scientists is the soul of technological innovation and a vital vehicle for higher education to achieve the goal of “fostering virtue and cultivating talents”. This paper takes the asymmetric synthesis research of Nobel laureate K. B. Sharpless as an entry point to explore how to integrate the spirit of scientists into the teaching of advanced organic chemistry courses, thereby achieving the synergistic educational objectives of knowledge transmission and value guidance. By uncovering the ideological and political elements embedded in the historical development of Sharpless reactions, we reconstruct teaching content and propose a curriculum-based ideological and political education practice framework centered on the trajectory of “scientific history case studies—extraction of ideological-political elements— cultivation of values”. This approach aims to provide insights for integrating ideological-political education into science and engineering curricula.