tRFAla-AGC-3-M8 attenuates neuroinflammation and neuronal damage in Alzheimer’s disease via the EphA7-ERK1/2-p70S6K signaling pathway
This study clarifies the specific role of tRF<sup>Ala-AGC-3-M8</sup> in AD pathology and offers a promising target for therapeutic interventions.
Authors
- Yudi Li (ORCID: https://orcid.org/0000-0002-0324-6888)
- Wanzhou Zhang (ORCID: https://orcid.org/0000-0001-8050-9496)
- Wanqing Chi
- Li Ling (ORCID: https://orcid.org/0000-0001-7238-9578)
- Zihao Deng (ORCID: https://orcid.org/0009-0000-2681-7180)
- Fangming Li
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s13195-025-01734-6
- Citations
- 8
- Primary Topic
- Axon Guidance and Neuronal Signaling
- Type
- article
- Field-Weighted Citation Impact
- 7.27