A network analysis of timing and conditions present at time of death for periviable infants (22+0–23+6 weeks) admitted to neonatal intensive care after receiving survival-focused care at birth

Where active, survival-focused care has been initiated, the response of the infant to intensive care and the likelihood of their survival emerges over a relatively short timeframe after admission. This lends support to a trial of therapy approach for suitable periviable infants balancing the need to avoid iatrogenic harm to infants who will ultimately die despite intensive care, whilst not denying them the chance at survival. Management of periviable deliveries requires coordinated parallel planning and a high-quality palliative care approach throughout.