Mammary Paget’s disease in a young woman: A rare occurrence

Mammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without pain, discharge, or inflammatory signs. Imaging revealed ductal dilation and nipple thickening, classified as BI-RADS 4, with MRI confirming additional suspicious findings. Histopathological analysis of a biopsy confirmed MPD associated with underlying ductal carcinoma in situ. This case underscores the importance of multimodal imaging and histopathology in diagnosing and managing this uncommon breast malignancy.

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Publication Details

Journal
Radiology Case Reports
Published
2025-05-15
DOI
https://doi.org/10.1016/j.radcr.2025.04.062
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
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article

Mammary Paget’s disease in a young woman: A rare occurrence

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Radiology Case Reports
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Mammary Paget’s disease in a young woman: A rare occurrence

Siham Oukassem, Siham El Haddad, Lina Belkouchi, Chaimae Abourak, Latifa Chat, Asmae Guennouni, Nazik Allali, Aya Laridi, Soukaina Bahha, Ouafaa Chahboune
article en

Abstract

Mammary Paget's disease (MPD) is a rare intraepithelial carcinoma involving the nipple-areolar complex, often linked to underlying ductal carcinoma. We report a case of a 47-year-old woman presenting with progressive swelling of the left nipple, without pain, discharge, or inflammatory signs. Imaging revealed ductal dilation and nipple thickening, classified as BI-RADS 4, with MRI confirming additional suspicious findings. Histopathological analysis of a biopsy confirmed MPD associated with underlying ductal carcinoma in situ. This case underscores the importance of multimodal imaging and histopathology in diagnosing and managing this uncommon breast malignancy.

Radiology Case ReportsVol. 20(8)
Mohammed V University (MA), Ibn Sina Hospital (KW)
Gender equality
Openalex Percentile: Top 80%
Cancer and Skin Lesions
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