Single-Cell Transcriptomics and Lineage Tracing Unveil Parallels in Lymphatic Muscle and Venous Smooth Muscle Development, Identity, and Function

Overall, our findings suggest that venous SMCs and LMCs derive from a related mesodermal progenitor and acquire a similar gene expression program that facilitates their contractile properties.

Authors

Sarah A. Mazzilli (ORCID: https://orcid.org/0000-0002-9187-2722)
Dennis Jones (ORCID: https://orcid.org/0000-0002-1401-9701)
Guillermo Arroyo‐Ataz (ORCID: https://orcid.org/0000-0002-3754-8841)
Julia C. Breda
Alejandra Carrasco Yagüe

Institutions

Boston University (US)

Publication Details

Journal: Arteriosclerosis Thrombosis and Vascular Biology
Published: 2025-05-15
DOI: https://doi.org/10.1161/atvbaha.125.322567
Citations: 2
Primary Topic: Lymphatic System and Diseases
Type: article
Field-Weighted Citation Impact: 2.09

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article

Single-Cell Transcriptomics and Lineage Tracing Unveil Parallels in Lymphatic Muscle and Venous Smooth Muscle Development, Identity, and Function

Sarah A. Mazzilli, Dennis Jones, Guillermo Arroyo‐Ataz, Julia C. Breda et al.

May 15, 2025

2 citations

Arteriosclerosis Thrombosis and Vascular Biology

Lymphatic System and Diseases

2.09

article

Single-Cell Transcriptomics and Lineage Tracing Unveil Parallels in Lymphatic Muscle and Venous Smooth Muscle Development, Identity, and Function

Sarah A. Mazzilli, Dennis Jones, Guillermo Arroyo‐Ataz, Julia C. Breda, Alejandra Carrasco Yagüe

May 15, 2025article en

2 citations

Abstract

Overall, our findings suggest that venous SMCs and LMCs derive from a related mesodermal progenitor and acquire a similar gene expression program that facilitates their contractile properties.

Arteriosclerosis Thrombosis and Vascular BiologyVol. 45(7)

Boston University (US)

Good health and well-being

Openalex Percentile: Top 12%

Lymphatic System and Diseases

2.09

DOI Open Access PDF OpenAlex

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Single-Cell Transcriptomics and Lineage Tracing Unveil Parallels in Lymphatic Muscle and Venous Smooth Muscle Development, Identity, and Function — Sarah A. Mazzilli, Dennis Jones, et al. · Arteriosclerosis Thrombosis and Vascular Biology (2025) | TGRS Research Map | TGRS