Regional Hypoperfusion Predicts White Matter Tract Degeneration in Recent Single Subcortical Infarcts
White matter tract degeneration has potential clinical value for indicating worse functional outcomes in RSSIs. Baseline regional hypoperfusion, especially with a lower contralateral cerebral blood flow ratio, independently predicts secondary white matter injury.
Authors
- Xin Cheng (ORCID: https://orcid.org/0000-0001-7816-0547)
- Ruosu Pan (ORCID: https://orcid.org/0009-0007-1857-2604)
- Le Cao (ORCID: https://orcid.org/0000-0002-0414-9932)
- Chen Ye (ORCID: https://orcid.org/0000-0003-2969-5486)
- Lan Hong (ORCID: https://orcid.org/0000-0002-4002-4627)
- Yi Ran Hu (ORCID: https://orcid.org/0000-0002-4891-9898)
- Yuying Yan (ORCID: https://orcid.org/0000-0002-0340-6597)
- Congjun Li (ORCID: https://orcid.org/0000-0003-1389-9820)
- Shuai Jiang (ORCID: https://orcid.org/0000-0003-2140-1535)
- Tang Yang (ORCID: https://orcid.org/0000-0001-9857-312X)
- Simiao Wu (ORCID: https://orcid.org/0000-0002-4557-7386)
- Anqi Zhang (ORCID: https://orcid.org/0000-0003-0360-5024)
- Bo Wu (ORCID: https://orcid.org/0000-0003-2067-9965)
- Kai Zhang (ORCID: https://orcid.org/0000-0001-5825-5733)
Institutions
- Sichuan University (CN)
- Fudan University (CN)
- West China Hospital of Sichuan University (CN)
- National Clinical Research (US)
- Huashan Hospital (CN)
- State Key Laboratory of Medical Neurobiology
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1161/jaha.124.040529
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71