Warnings on the inclusion of cluster randomized trials in meta-analysis: results of a simulation study
Ignoring clustering in CRTs lead to inflated false-positive conclusions about the efficacy of treatments, highlighting the need for caution and proper analytical methods when incorporating CRTs into meta-analyses.
Authors
- Joseph Alvin Santos (ORCID: https://orcid.org/0000-0002-8195-3887)
- Gian Luca Di Tanna (ORCID: https://orcid.org/0000-0002-5470-3567)
- Emilia Riggi (ORCID: https://orcid.org/0000-0001-8878-7060)
Institutions
- University of Applied Sciences and Arts of Southern Switzerland (CH)
- The George Institute for Global Health (AU)
Publication Details
- Journal
- BMC Medical Research Methodology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s12874-025-02586-2
- Primary Topic
- Meta-analysis and systematic reviews
- Type
- article
- Field-Weighted Citation Impact
- 0.00