Investigating pulmonary inflammation and injury after progressive systemic inflammation in preterm fetal sheep
Intravenous administration of LPS did not cause fetal lung inflammation and injury assessed 4 days after LPS infusions commenced. Direct exposure to endotoxins within the lungs may be necessary to induce inflammation and injury in the fetal lungs.
Authors
- Stuart B. Hooper (ORCID: https://orcid.org/0000-0003-1676-4825)
- Robert Galinsky (ORCID: https://orcid.org/0000-0002-6374-9372)
- Graeme R. Polglase (ORCID: https://orcid.org/0000-0002-8906-614X)
- E Vandenberg (ORCID: https://orcid.org/0000-0002-2458-1618)
- Alison M. Thiel
- Lu Hong (ORCID: https://orcid.org/0000-0003-3873-9276)
- Valerie A. Zahra
- Seamus B. Kelly
Institutions
- Hudson Institute of Medical Research (AU)
- Monash University (AU)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fphys.2025.1542613
- Citations
- 1
- Primary Topic
- Preterm Birth and Chorioamnionitis
- Type
- article
- Field-Weighted Citation Impact
- 1.35