Rectal Angiosarcoma: A Case Report Highlighting Multidisciplinary Strategies for Rare Malignancies

<b>Background and Clinical Significance</b>: Rectal angiosarcoma is an exceptionally rare and aggressive malignancy, comprising less than 1% of soft tissue sarcomas. This case highlights the diagnostic and therapeutic challenges posed by this disease, and the lack of established guidelines emphasizing the importance of a multidisciplinary approach. <b>Case Presentation</b>: A 41-year-old male firefighter, with a history of heavy smoking, presented with lower abdominal pain, rectal bleeding, and urgency. Imaging and biopsy confirmed rectal angiosarcoma, stage IIIB. The patient underwent IMRT/VMAT radiation therapy followed by laparoscopic rectal amputation with colostomy. No sign of recurrence or metastatic disease was present on follow-up imaging. <b>Conclusions</b>: This case underlines the importance of a personalized treatment strategy and multidisciplinary collaboration in rare malignancies. Early diagnosis and cooperation across specialties are critical for achieving the best possible outcomes.