Evaluation of epigenetic silencing of the miR-139-5p gene in the pathogenesis of colorectal cancer and its diagnostic biomarker capability in plasma samples
Hyper-methylation of miR-139-5p could be suggested as high accuracy diagnostic biomarker for the detection of CRC in plasma samples, pending further validation with large prospective studies.
Authors
- Masoud Asefi
- Massoud Saidijam (ORCID: https://orcid.org/0000-0001-8910-556X)
- Ali Reza Soltanian (ORCID: https://orcid.org/0000-0002-7483-3502)
- Ali Mahdavinezhad (ORCID: https://orcid.org/0000-0002-1314-8229)
- Nayebali Rezvani (ORCID: https://orcid.org/0000-0001-6153-0345)
- Alireza Khalilian (ORCID: https://orcid.org/0000-0003-3086-6887)
Institutions
- Hamedan University of Medical Sciences (IR)
- Kermanshah University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s12885-025-14290-x
- Citations
- 1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Hamadan University of Medical Sciences
- Kermanshah University of Medical Sciences