An exploratory study on the metagenomic and proteomic characterization of hypothyroidism in the first half of pregnancy and correlation with Th1/Th2 balance
Increased <i>P. vulgatus</i> and <i>B. fragilis</i>, decreased DGKK and S10A8 proteins, and a left shift in the Th1/Th2 balance in patients with hypothyroidism in the first half of pregnancy may be associated with the development of the disease.
Authors
- Yajuan Xu (ORCID: https://orcid.org/0000-0003-0819-1369)
- Jingjing Li (ORCID: https://orcid.org/0000-0002-9882-7377)
- Zongzong Sun (ORCID: https://orcid.org/0000-0002-6076-5780)
- Yixin Wang (ORCID: https://orcid.org/0000-0003-4324-2408)
- Miao Zhang (ORCID: https://orcid.org/0000-0002-4242-005X)
- Chenchen Zhang (ORCID: https://orcid.org/0000-0001-8563-5002)
- Pengkun Lin
Institutions
- Third Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3389/fimmu.2025.1500866
- Citations
- 1
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29
Funders
- Zhengzhou University