Comparison of dried blood spot (DBS) and plasma HIV-1 viral load measurements using Roche COBAS AmpliPrep/COBAS TaqMan assay, Northwest Ethiopia

The findings of the current study suggested that DBS samples could be considered as an alternative approach for periodic monitoring of HIV-1 viral loads to scale-up the HIV diagnosis and treatment coverage, particularly in areas with limited laboratory settings due to minimal invasive blood collection, higher stability at room temperature or ease of transportation, and decentralized sample collection approaches.

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Publication Details

Journal
Virology Journal
Published
2025-05-15
DOI
https://doi.org/10.1186/s12985-025-02762-2
Primary Topic
HIV Research and Treatment
Type
article
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article

Comparison of dried blood spot (DBS) and plasma HIV-1 viral load measurements using Roche COBAS AmpliPrep/COBAS TaqMan assay, Northwest Ethiopia

Nega Berhane, Firehiwot Kebede, Gezahegn Bewket, Tadelo Wondmagegn et al.
1 links
Virology Journal
HIV Research and Treatment
article

Comparison of dried blood spot (DBS) and plasma HIV-1 viral load measurements using Roche COBAS AmpliPrep/COBAS TaqMan assay, Northwest Ethiopia

Nega Berhane, Firehiwot Kebede, Gezahegn Bewket, Tadelo Wondmagegn, Muluneh Assefa, Getu Girmay, Mulualem Lemma
article en

Abstract

The findings of the current study suggested that DBS samples could be considered as an alternative approach for periodic monitoring of HIV-1 viral loads to scale-up the HIV diagnosis and treatment coverage, particularly in areas with limited laboratory settings due to minimal invasive blood collection, higher stability at room temperature or ease of transportation, and decentralized sample collection approaches.

Virology JournalVol. 22(1)
University of Gondar (ET)
Openalex Percentile: Top 88%
HIV Research and Treatment
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