Anti-aging klotho protein. Associations with sleep patterns in obstructive sleep apnea: A pilot study
Our results show a decrease in anti-aging klotho protein levels in patients with OSAS, which is a precipitating factor for premature aging. The klotho protein's positive correlation with sleep patterns and its negative relationship with the main trigger mechanism, intermittent hypoxia, demonstrates the role of OSAS in early and accelerated cellular aging.
Authors
- O. N. Berdina (ORCID: https://orcid.org/0000-0003-0930-6543)
- V V Madaev (ORCID: https://orcid.org/0000-0002-9847-2529)
- С. И. Колесников (ORCID: https://orcid.org/0000-0003-2124-6328)
- Л. Ф. Шолохов (ORCID: https://orcid.org/0000-0003-3588-6545)
- Мадаева Ирина Михайловна (ORCID: https://orcid.org/0000-0003-3423-7260)
- Л. И. Колесникова (ORCID: https://orcid.org/0000-0003-3354-2992)
- A.A. Pytkina
Institutions
- Scientific Center of Family Health Problems and Human Reproduction (RU)
Publication Details
- Journal
- S S Korsakov Journal of Neurology and Psychiatry
- Published
- 2025-05-15
- DOI
- https://doi.org/10.17116/jnevro202512505298
- Citations
- 1
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16