Evaluation of Optimal Sequential Treatment Patterns and Clinical Outcomes in Patients With Advanced Urothelial Carcinoma Treated With First‐Line Platinum‐Based Chemotherapy: A Multicenter Collaborative Study
This study emphasizes the prognostic importance of achieving EV therapy and the role of maintenance avelumab in improving outcomes for la/mUC patients with one or more risk factors after 1 L-PBC. Combining EV with pembrolizumab is a promising first-line treatment, and 1 L-PBC remains a viable option for selected patients.
Authors
- Masaki Hashimoto (ORCID: https://orcid.org/0000-0002-0396-8223)
- Fumihiko Urabe (ORCID: https://orcid.org/0000-0002-2599-8183)
- Kosuke Iwatani (ORCID: https://orcid.org/0000-0001-5428-852X)
- Yuki Takiguchi (ORCID: https://orcid.org/0009-0002-0439-1670)
- Naoki Uchida (ORCID: https://orcid.org/0000-0002-4220-9625)
- Jun Miki (ORCID: https://orcid.org/0000-0002-4638-8640)
- Shunsuke Tsuzuki
- Masaya Murakami (ORCID: https://orcid.org/0000-0002-1268-6615)
- Kojiro Tashiro
- Sotaro Kayano (ORCID: https://orcid.org/0009-0001-0895-1551)
- Y Taneda
- Takashi Ohtsuka (ORCID: https://orcid.org/0000-0002-8039-9159)
- Shota Kawano
- Yu Imai (ORCID: https://orcid.org/0000-0003-0971-4205)
- Takahiro Kimura (ORCID: https://orcid.org/0000-0002-5673-1553)
- Minoru Nakazono
- Mahito Atsuta
- Hiroki Yamada
- Ken Shibata
- Toshihiro Yamamoto
Institutions
- Jikei University School of Medicine (JP)
- Katsushika Medical Center (JP)
- Tokyo-Kita Medical Center (JP)
- Kameda Medical Center (JP)
- The Jikei University Hospital (JP)
- Fujieda Municipal General Hospital (JP)
- Jikei University Kashiwa hospital (JP)
- Fuji Heavy Industries Health Insurance Society Ota Memorial Hospital (JP)
- JR Tokyo General Hospital (JP)
- Tsurugi Hospital (JP)
Publication Details
- Journal
- International Journal of Urology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1111/iju.70113
- Citations
- 3
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.02