LC-MS/MS determination of trazodone in human plasma and its pharmacokinetic study in healthy Chinese
The validated LC-MS/MS method proved reliable for trazodone quantification. The observed food effects on absorption suggest clinical dosing should consider administration conditions to ensure optimal therapeutic outcomes.
Authors
- Shengbai Zhang (ORCID: https://orcid.org/0000-0003-0833-5860)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-8835-1993)
- Qunan Cheng
- Jie Lin (ORCID: https://orcid.org/0009-0004-0293-6192)
- Yonghua Yu (ORCID: https://orcid.org/0000-0002-8752-9956)
- Kaiwei Luo
- Danrui Liu (ORCID: https://orcid.org/0000-0002-3313-3497)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1080/17576180.2025.2506349
- Citations
- 1
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.56