Five new phenolics from the red resin of <i>Dracaena cochinchinensis</i>
Five undescribed phenolics including three new flavonoids (<b>1</b>-<b>3</b>), one new flavone glycoside (<b>4</b>) and one neolignan (<b>5</b>), together with seven known compounds were isolated from the resins of <i>Dracaena cochinchinensis</i> (Chinese dragon's blood). Their structures were elucidated based on detailed spectroscopic analysis, including 1D, 2D NMR, mass spectrometry, and electronic circular dichroism (ECD) data analysis. In addition, biological evaluation of compounds <b>1</b>-<b>5</b> on anti-renal fibrotic activities were conducted, and the results showed that compounds <b>1a</b>, <b>2</b>, and <b>5</b> display anti-renal fibrotic activities in TFG-<i>β</i> induced NRK-52e cells.
Authors
- Hong Shi
- Nan Lin (ORCID: https://orcid.org/0000-0002-8680-2455)
- Yong‐Xian Cheng (ORCID: https://orcid.org/0000-0002-1343-0806)
Institutions
- Shenzhen University (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Asian Natural Products Research
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1080/10286020.2025.2497279
- Primary Topic
- Phytochemical Studies and Bioactivities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Fund for Distinguished Young Scholars