Analysis of Gut-Homing Receptors in Circulating Mucosal-Associated Invariant T Cells and Their Presence in Synovial Tissue From Patients With Axial Spondyloarthritis
MAIT cells were activated and expressed Gut-Homing receptors, indicating their potential involvement in the gut-joint axis in axSpA. MAIT cell frequency and function were reduced by TNF blockade. MAIT cells could be found in synovial tissue in patients with axSpA.
Authors
- Maxime Samson (ORCID: https://orcid.org/0000-0002-6547-232X)
- Caroline Laheurte (ORCID: https://orcid.org/0000-0002-1364-4556)
- Charline Vauchy
- Eléonore Gravelin
- Éric Toussirot (ORCID: https://orcid.org/0000-0002-6228-1464)
- Philippe Saas (ORCID: https://orcid.org/0000-0002-8857-9939)
- Franck Monnien (ORCID: https://orcid.org/0000-0002-2799-3730)
- André Ramon (ORCID: https://orcid.org/0000-0002-7289-7916)
- Marc Puyraveau
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire de Besançon (FR)
- Methodology and Quality of Life Unit in Oncology (FR)
- CHU Dijon Bourgogne (FR)
- Établissement Français du Sang (FR)
- Université Marie et Louis Pasteur (FR)
- Université Grenoble Alpes (FR)
- Université de Franche-Comté (FR)
Publication Details
- Journal
- The Journal of Rheumatology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.3899/jrheum.2024-1294
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.77