Genome-based analyses from four clinically-isolated strains refined the taxonomy of Proteus genomosp. 6 and revealed their underestimated role in gastrointestinal diseases
Our study highlights inaccuracies in the taxa classification of Proteus species under clinical settings, underscoring the necessity of using genomic-based taxonomic assignment methods. We revealed that the prevalence of Proteus genomosp. 6 in clinical infections has likely been underestimated. Furthermore, given the resistance-gene absence and their sensitivity to aminoglycosides, aminoglycosides may serve as a promising first-line treatment option for infections caused by this species.
Authors
- Li Huang (ORCID: https://orcid.org/0000-0003-0741-4903)
- Jing He (ORCID: https://orcid.org/0000-0002-7249-4746)
- Zhou Zeng (ORCID: https://orcid.org/0000-0002-3298-3481)
- Xueqing Liu (ORCID: https://orcid.org/0000-0002-3227-7448)
- Zhiyun Zhang (ORCID: https://orcid.org/0000-0001-7513-9427)
- Yao Peng (ORCID: https://orcid.org/0000-0001-8992-8814)
- Xunchao Cai (ORCID: https://orcid.org/0000-0002-1830-1464)
Institutions
- Hunan University of Traditional Chinese Medicine (CN)
- Northeast Agricultural University (CN)
- Hunan University of Science and Engineering (CN)
- Ezhou Central Hospital (CN)
- Hangzhou Vocational and Technical College (CN)
- University of South China (CN)
Publication Details
- Journal
- Gut Pathogens
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1186/s13099-025-00701-8
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00