Gastrointestinal Barrier Disruption in Post‐<scp>COVID</scp> Syndrome Fatigue Patients
We propose that the viral infection disrupts pathways related to the innate immune response and GI barrier function, evidenced by intestinal low-grade inflammation and GI barrier leakage. Monitoring GI symptoms and markers before, during, and after SARS-CoV-2 infection is crucial for identifying predictive clinical phenotypes in PCS. Understanding the interaction between viral infections, immune responses, and gut integrity could lead to more effective diagnostic and treatment strategies, ultimately reducing the burden on PCS patients.
Authors
- Joana Séneca (ORCID: https://orcid.org/0000-0003-3951-3674)
- Johanna Rohrhofer (ORCID: https://orcid.org/0000-0002-2783-2099)
- Michael Stingl (ORCID: https://orcid.org/0009-0004-7220-0658)
- Larissa Koidl (ORCID: https://orcid.org/0000-0001-9974-7929)
- Eva Untersmayr (ORCID: https://orcid.org/0000-0002-1963-499X)
- Sonja Zehetmayer (ORCID: https://orcid.org/0000-0001-6863-7997)
- Petra Pjevac (ORCID: https://orcid.org/0000-0001-7344-302X)
- Johannes Schweighardt
- Viktoria Wolflehner
Institutions
- University of Vienna (AT)
- Medical University of Vienna (AT)
Publication Details
- Journal
- Allergy
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1111/all.16593
- Citations
- 4
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- Universität Wien