Long-Chain Omega-3 Polyunsaturated Fatty Acids and Sarcopenia

Sarcopenia is the age-related loss of muscle mass, strength, and function that predisposes older adults to impaired mobility, risk of falls, greater disability, and poor quality of life. From a nutritional perspective, sarcopenia treatment and prevention strategies include adequate calorie intake with a special emphasis on protein and amino acids. Recent evidence suggests that long-chain n -3 polyunsaturated fatty acids, particularly eicosapentaenoic acid and docosahexaenoic acid, may be a complimentary therapeutic target to improve sarcopenia-related outcomes such as muscle mass, strength, and function. This review aims to critically evaluate the scientific evidence exploring the influence of eicosapentaenoic acid + docosahexaenoic acid on sarcopenia-related outcomes as a brief primer for nutrition professionals.