Disparities, trends, and projections of cancer mortality burden related to high body mass index in China from 2005 to 2030
High body mass index (BMI), defined as a BMI greater than or equal to 20-25 kg/m<sup>2</sup>, is considered a rapid-increased risk factor for cancer. Based on comparative risk assessment framework, we elaborate the mortality burden of cancers attributable to high BMI in China. In 2018, we estimated that there were 85.19 thousand cancer-related deaths and 2,220.01 thousand cancer-related years of life lost (YLLs) attributable to high BMI in China. Of these, 62.14 thousand deaths and 1,698.81 thousand YLLs were from males. With higher socioeconomic levels, the burden generally increases initially and then decreases. By 2030, the projected age-standardized mortality rate attributable to high BMI in China will be 6.67 per 100,000 people, increased by 3.25% from that in 2005. In summary, the swift increase and substantial disparities in the cancer burden attributable to high BMI underscore the urgent need for evidence-based policies and interventions in China.
Authors
- Xue Qin Yu (ORCID: https://orcid.org/0000-0001-8638-7979)
- Zengwu Wang (ORCID: https://orcid.org/0000-0003-1613-5076)
- Yujie Zhang (ORCID: https://orcid.org/0000-0001-9249-2601)
- Yixin Tian (ORCID: https://orcid.org/0009-0003-0102-2906)
- Xuyan Pei (ORCID: https://orcid.org/0009-0006-6648-6850)
- Limin Wang (ORCID: https://orcid.org/0000-0003-2239-6117)
- Zhenping Zhao (ORCID: https://orcid.org/0000-0003-4227-3034)
- Maigeng Zhou (ORCID: https://orcid.org/0000-0001-6402-6347)
- Xin Wang (ORCID: https://orcid.org/0000-0002-8916-8541)
- Mei Zhang (ORCID: https://orcid.org/0000-0002-4284-555X)
- Peng Yin (ORCID: https://orcid.org/0000-0002-5515-2824)
- Congyi Zheng
- Yuna He
- Chenye Chang
- Yuehui Fang
- Xue Cao
- Nuerguli Tuerdi
Institutions
- Chinese Center For Disease Control and Prevention (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- National Center for Chronic and Noncommunicable Disease Control and Prevention (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Cell Reports Medicine
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1016/j.xcrm.2025.102137
- Citations
- 2
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- National Health Commission of the People's Republic of China
- National Key Research and Development Program of China