Engineered proxies and the illusion of de-extinction

The recent creation of dire wolf-like canids by Colossal Biosciences marks a technical achievement in genome editing and synthetic embryology. But the project also demands a reevaluation of what we mean by "de-extinction"-and whether a phenotypic approximation constitutes species restoration.

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Publication Details

Journal
Stem Cell Reports
Published
2025-05-15
DOI
https://doi.org/10.1016/j.stemcr.2025.102505
Citations
4
Primary Topic
Neuroethics, Human Enhancement, Biomedical Innovations
Type
article
Field-Weighted Citation Impact
5.72

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article

Engineered proxies and the illusion of de-extinction

Duško Ilić
4 citations
Stem Cell Reports
Neuroethics, Human Enhancement, Biomedical Innovations
5.72
article

Engineered proxies and the illusion of de-extinction

Duško Ilić
article en
4 citations

Abstract

The recent creation of dire wolf-like canids by Colossal Biosciences marks a technical achievement in genome editing and synthetic embryology. But the project also demands a reevaluation of what we mean by "de-extinction"-and whether a phenotypic approximation constitutes species restoration.

Stem Cell ReportsVol. 20(6)
King's College London (GB)
King's College London, Guy's and St Thomas' NHS Foundation Trust
Climate action
Openalex Percentile: Top 4%
Neuroethics, Human Enhancement, Biomedical Innovations
5.72
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Engineered proxies and the illusion of de-extinction — Duško Ilić · Stem Cell Reports (2025) | TGRS Research Map | TGRS