Clinical case of combination of Libman–Sacks endocarditis, pericarditis and myocarditis in a patient with systemic lupus erythematosus

A rare case of a combination of conditions such as myocarditis, Libman–Sachs endocarditis and pericarditis in a patient with SLE is described. Systemic lupus erythematosus (SLE) is a genetically determined, systemic autoimmune disease with a relapsing-remitting course, characterized by the formation of autoantibodies and immune complexes that mediate immune inflammation and tissue damage. The prevalence of SLE, according to studies conducted throughout the world, varies from 4 to 250 cases per 100 thousand adults. In the Russian Federation, according to the V.A. Nasonova Research Institute of Rheumatology, the prevalence of SLE is 9.0–20.6 cases per 100 thousand people. The most common cardiac complications of SLE include myocarditis, pericarditis, Libman–Sachs endocarditis (LSE), pulmonary arterial hypertension, cardiosclerosis, myocardial infarction and premature development of atherosclerosis. The presence of these conditions significantly increases the mortality rate of patients with SLE. This paper describes a rare case of a combination of conditions such as myocarditis, ELS and pericarditis in a patient with SLE.