Evaluation of the Safety, Pharmacokinetics, and Antitumor Activity of Tusamitamab Ravtansine in Patients With Nonsquamous NSCLC With High or Moderate Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5

Tusamitamab ravtansine demonstrated a favorable safety profile, objective responses, and antitumor activity in patients with high CEACAM5-expressing NSq NSCLC.

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Publication Details

Journal
JTO Clinical and Research Reports
Published
2025-05-15
DOI
https://doi.org/10.1016/j.jtocrr.2025.100844
Citations
3
Primary Topic
Radiopharmaceutical Chemistry and Applications
Type
article
Field-Weighted Citation Impact
4.08
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article

Evaluation of the Safety, Pharmacokinetics, and Antitumor Activity of Tusamitamab Ravtansine in Patients With Nonsquamous NSCLC With High or Moderate Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5

Nathalie Fagniez, María Vieito, Víctor Moreno, Carole Hélissey et al.
3 citations
JTO Clinical and Research Reports
Radiopharmaceutical Chemistry and Applications
4.08
article

Evaluation of the Safety, Pharmacokinetics, and Antitumor Activity of Tusamitamab Ravtansine in Patients With Nonsquamous NSCLC With High or Moderate Expression of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5

Nathalie Fagniez, María Vieito, Víctor Moreno, Carole Hélissey, Charles Ricordel, Christine Soufflet, Anas Gazzah, Mustapha Chadjaa, François Ghiringhelli, Luis Paz‐Ares, Emiliano Calvo, Nina Masson, Byoung Chul Cho, Fabrice Barlési, Jin-Soo Kim, Sophie Cousin, Dong-Wan Kim, Anne-Laure Bauchet, Antoine Italiano
article en
3 citations

Abstract

Tusamitamab ravtansine demonstrated a favorable safety profile, objective responses, and antitumor activity in patients with high CEACAM5-expressing NSq NSCLC.

JTO Clinical and Research ReportsVol. 6(10)
Seoul National University (KR), Université de Bordeaux (FR), Yonsei University (KR), Université Paris-Saclay (FR), Institut Gustave Roussy (FR), Seoul National University Hospital (KR), Sanofi (France) (FR), Centre Georges François Leclerc (FR), SNUH SMG-SNU Boramae Medical Center (KR), Vall d'Hebron Hospital Universitari (ES), Hospital Universitario Fundación Jiménez Díaz (ES), Institut Bergonié (FR), Vall d'Hebron Institute of Oncology (ES)
Good health and well-being
Openalex Percentile: Top 6%
Radiopharmaceutical Chemistry and Applications
4.08
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