A Century of Hypomethylating Agent: A Remarkable Response to Azacitidine Monotherapy for Relapsed Acute Myeloid Leukemia – A Case Report
To our knowledge, no other reports describe relapsed AML treated with HMA monotherapy achieving such exceptional survival. The remarkable response duration suggests mechanisms beyond cytotoxicity. Further research should explore HMA monotherapy's effects across AML subgroups, including inv(16).
Authors
- Gina Keiffer
- Amry Majeed
- Chetan Jeurkar (ORCID: https://orcid.org/0000-0001-6127-2251)
- Lindsay Wilde (ORCID: https://orcid.org/0000-0002-7482-7970)
- Margaret Kasner (ORCID: https://orcid.org/0000-0001-8616-744X)
Institutions
- Thomas Jefferson University (US)
- Sidney Kimmel Cancer Center (US)
Publication Details
- Journal
- Case Reports in Oncology
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1159/000545569
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00