Clinical application of wet healing in the treatment of aplasia cutis congenita on scalp: A case report

Aplasia cutis congenita (ACC) is a rare congenital abnormality characterized by localized defects in the skin at birth. It commonly affects the scalp and coexists with cranial bone defects, which increase the risk of infection and bleeding. This risk is particularly heightened for midline lesions. There is currently no clear indication for surgical or conservative treatment, therefore, it would be beneficial to seek scientific support in order to determine the optimal treatment strategies. This case report describes a newborn with ACC who had a significant defect measuring 4 cm in diameter, along with cranial bone defects. Following wet and dry healing treatments, the wound healed by the 10th day. The defect showed significant healing within just one week, with the wound progressing from a moist to a dry healing process. The early implementation of moist wound healing therapy along with securing oil gauze with an elastic cap, followed by the application of a dry healing method to expedite crust formation, could possibly serve as the basic wound care therapy for similar ACC cases presenting with cranial defects. • The wound showed significant healing within one week, transitioning from moist to dry wound healing. • Early implementation of moist wound healing followed by dry healing may be a beneficial wound care strategy for similar ACC cases with cranial defects.

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Publication Details

Journal
Medical Reports
Published
2025-05-15
DOI
https://doi.org/10.1016/j.hmedic.2025.100251
Primary Topic
Skin and Cellular Biology Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Clinical application of wet healing in the treatment of aplasia cutis congenita on scalp: A case report

Guangliang Bi, Antônio Ximenes, Jian Yang, Weihua Liao et al.
Medical Reports
Skin and Cellular Biology Research
article

Clinical application of wet healing in the treatment of aplasia cutis congenita on scalp: A case report

Guangliang Bi, Antônio Ximenes, Jian Yang, Weihua Liao, Jing Ding
article en

Abstract

Aplasia cutis congenita (ACC) is a rare congenital abnormality characterized by localized defects in the skin at birth. It commonly affects the scalp and coexists with cranial bone defects, which increase the risk of infection and bleeding. This risk is particularly heightened for midline lesions. There is currently no clear indication for surgical or conservative treatment, therefore, it would be beneficial to seek scientific support in order to determine the optimal treatment strategies. This case report describes a newborn with ACC who had a significant defect measuring 4 cm in diameter, along with cranial bone defects. Following wet and dry healing treatments, the wound healed by the 10th day. The defect showed significant healing within just one week, with the wound progressing from a moist to a dry healing process. The early implementation of moist wound healing therapy along with securing oil gauze with an elastic cap, followed by the application of a dry healing method to expedite crust formation, could possibly serve as the basic wound care therapy for similar ACC cases presenting with cranial defects. • The wound showed significant healing within one week, transitioning from moist to dry wound healing. • Early implementation of moist wound healing followed by dry healing may be a beneficial wound care strategy for similar ACC cases with cranial defects.

Medical ReportsVol. 13
Nanfang Hospital (CN), Southern Medical University (CN)
Natural Science Foundation of Guangdong Province
Zero hunger
Openalex Percentile: Top 89%
Skin and Cellular Biology Research
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Clinical application of wet healing in the treatment of aplasia cutis congenita on scalp: A case report — Guangliang Bi, Antônio Ximenes, et al. · Medical Reports (2025) | TGRS Research Map | TGRS