Exploring the Link Between ITGB3 Gene Polymorphism and Diastolic Dysfunction in Arterial Hypertension Patients

Background: Arterial hypertension (AH) is a significant risk factor for cardiovascular diseases (CVDs), including myocardial infarction and stroke. The ITGB3 gene polymorphism, particularly T1565C (rs5918), has been implicated in various cardiovascular conditions, suggesting a potential role in diastolic dysfunction (DD) among AH patients. Objectives: The clinical-genetic relationship was studied between ITGB3 gene polymorphisms and DD in Azerbaijani patients with AH, with or without ischemic heart disease (IHD) and type 2 diabetes (T2D) mellitus. Methods: The study included 100 Azerbaijani [...]

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Publication Details

Journal
International Journal of Cardiovascular Sciences
Published
2025-01-01
DOI
https://doi.org/10.36660/ijcs.20240144
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Exploring the Link Between ITGB3 Gene Polymorphism and Diastolic Dysfunction in Arterial Hypertension Patients

Vafa Nazirova, Ismail Gafarov, Zumrud Ismibayli, Faiq Guliyev et al.
International Journal of Cardiovascular Sciences
Cardiovascular Function and Risk Factors
article

Exploring the Link Between ITGB3 Gene Polymorphism and Diastolic Dysfunction in Arterial Hypertension Patients

Vafa Nazirova, Ismail Gafarov, Zumrud Ismibayli, Faiq Guliyev, Konstantinos Kyriazis
article en

Abstract

Background: Arterial hypertension (AH) is a significant risk factor for cardiovascular diseases (CVDs), including myocardial infarction and stroke. The ITGB3 gene polymorphism, particularly T1565C (rs5918), has been implicated in various cardiovascular conditions, suggesting a potential role in diastolic dysfunction (DD) among AH patients. Objectives: The clinical-genetic relationship was studied between ITGB3 gene polymorphisms and DD in Azerbaijani patients with AH, with or without ischemic heart disease (IHD) and type 2 diabetes (T2D) mellitus. Methods: The study included 100 Azerbaijani [...]

International Journal of Cardiovascular SciencesVol. 38
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Cardiovascular Function and Risk Factors
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