Evaluation of the efficacy of Saplint plus roll-on in the treatment of acute myalgia: A prospective, open-label, single-arm clinical trial

Background: Myalgia, or muscle pain, is a prevalent condition with diverse etiologies ranging from overuse to viral infections. Conventional treatments, while effective, often carry risks of adverse effects with prolonged use. Saplint Plus Roll-On, an Ayurvedic formulation, offers a non-invasive, herbal approach to pain relief. Objective: To evaluate the efficacy of Saplint Plus Roll-On in the management of acute myalgia over a 7-day period. Methods: A single-arm, open-label, prospective clinical trial was conducted involving 100 patients diagnosed with acute myalgia. Participants applied Saplint Plus Roll-On three times daily. Efficacy was assessed using the Visual Analog Scale (VAS), Patient Global Assessment, and Modified Oswestry Disability Index (ODI). Results: The mean VAS score reduced from 7.5 at baseline to 2.0 on Day 7 (73% reduction, p < 0.01). The mean ODI score improved from 45.2 to 25.3 (p < 0.01). No adverse events were reported. Conclusion: Saplint Plus Roll-On significantly reduced pain and improved functional ability in patients with acute myalgia, offering an effective alternative to conventional analgesics.