Clinicohematological and molecular analysis of hemoglobin D syndrome and unknown variants in the hemoglobinopathy spectrum of Sindh, Pakistan
Hb D Punjab is the most prevalent hemoglobin variant in Sindh, Pakistan, followed by HbS and HbQ. Molecular analysis is essential for accurate diagnosis and identifying rare variants. Integrating HbD detection into screening programmes and genetic counselling can help prevent hemoglobinopathies. (S1 Abstract Graphic).
Authors
- Ali Raza Rajput (ORCID: https://orcid.org/0000-0002-3710-4810)
- Ali Muhammad Waryah (ORCID: https://orcid.org/0000-0002-2596-9032)
- Ikram Din Ujjan
- Feriha Fatima Khidri (ORCID: https://orcid.org/0000-0003-0319-8772)
- Sunila Tashfeen (ORCID: https://orcid.org/0000-0002-2023-4846)
- Hina Shaikh (ORCID: https://orcid.org/0000-0001-7713-5884)
- Muhammad Arif Sadiq
Institutions
- Liaquat University of Medical & Health Sciences (PK)
- Pakistan Army (PK)
- Military Hospital (PK)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-15
- DOI
- https://doi.org/10.1371/journal.pone.0320354
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00